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MedPage Today Allergy & Immunology - Recent Medical Updates

Asthma Sufferers Could Be at Greater Risk if Trump Cuts Health Program
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115939.jpg"/> (MedPage Today) -- Esther Bejarano's son was 11 months old when asthma landed him in the hospital. She didn't know what had triggered his symptoms -- neither she nor her husband had asthma -- but she suspected it was the pesticides sprayed...


EPA Moves to Roll Back Rules Projected to Save Thousands of Lives and Billions of $$
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115921.jpg"/> (MedPage Today) -- When the head of the Environmental Protection Agency (EPA) announced a wide-ranging rollback of environmental regulations, he said it would put a "dagger through the heart of climate-change religion" and introduce a "Golden Age...


Pulmonary Rehabilitation for COPD Pushes Forward
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115915.jpg"/> (MedPage Today) -- Home-based pulmonary rehabilitation has been slowly gaining momentum for chronic obstructive pulmonary disease (COPD), but access is still a challenge. "The science shows that there is greater benefit from pulmonary rehab than...


Easing Airway Assaults in COPD
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115914.jpg"/> (MedPage Today) -- Both indoor and outdoor air quality impact chronic obstructive pulmonary disease (COPD), which opens up a large avenue to work with patients to improve their outcomes. For COPD patients, the adage holds true: "the first way...


Is It Really Time to Say Goodbye to Benadryl?
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115904.jpg"/> (MedPage Today) -- A paper that calls for saying a "final goodbye" to diphenhydramine -- best known as Benadryl -- has physicians talking on social media. Published in the World Allergy Organization Journal, the paper gives several reasons...


A Yellow Warning: This Year’s Pollen Surge Was More Than Just a Nuisance
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115889.jpg"/> (MedPage Today) -- If you live almost anywhere in the U.S., you've probably noticed it: the dusting of yellow powder on your car, your windowsill, and even your eyelashes. This spring, Americans have been engulfed by an overwhelming wave of pollen...


Parenting Training Reduces Healthcare Needs for Kids With Asthma Plus ADHD
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115872.jpg"/> (MedPage Today) -- A parenting intervention for families of children with comorbid asthma and attention-deficit-hyperactivity disorder (ADHD) reduced healthcare needs for these children, a study from China showed. The acceptance and commitment...


FDA Approves Mepolizumab for COPD
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115751.jpg"/> (MedPage Today) -- The FDA approved mepolizumab (Nucala) for adults with inadequately controlled chronic obstructive pulmonary disease (COPD), drugmaker GSK announced on Thursday. Labeling for the interleukin-5 (IL-5) antagonist stipulates use...


Tezepelumab Cuts Oral Corticosteroid Use in Severe Asthma
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115672.jpg"/> (MedPage Today) -- Most patients with severe asthma substantially reduced or even discontinued oral corticosteroid use with addition of tezepelumab (Tezspire) in the single-arm WAYFINDER trial. At both 28 and 52 weeks, 88.9% of patients dropped...


FDA Issues Safety Alert on Popular Allergy Drugs
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115669.jpg"/> (MedPage Today) -- The FDA warned that some people develop severe itching, or pruritus, after stopping long-term use of the antihistamines cetirizine (Zyrtec) or levocetirizine (Xyzal). Prescribing information for the oral allergy drugs -- which...


Combo Inhaler Better for Mild Asthma
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115646.jpg"/> (MedPage Today) -- As-needed use of a metered-dose inhaler with albuterol plus budesonide (Airsupra) lowered the risk of severe exacerbations compared with albuterol alone for people with normally mild asthma, the phase III BATURA trial showed...


Adding CT, Symptoms Improves COPD Diagnosis
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115637.jpg"/> (MedPage Today) -- Incorporating chest CT imaging and respiratory symptoms into the chronic obstructive pulmonary disease (COPD) diagnostic schema improved identification of individuals with poor respiratory outcomes, two longitudinal cohorts showed...


Mucus-Plugged Airways Linked to COPD Outcomes
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115584.jpg"/> (MedPage Today) -- Airway-blocking mucus plugs were associated with a faster decrease in lung function in chronic obstructive pulmonary disease (COPD), a longitudinal study showed. Decrease in the forced expiratory volume in 1 second (FEV1) marking...


Severe Cases of Virus Tied to Polio-like Paralysis Often Occurs in Healthy Kids
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115507.jpg"/> (MedPage Today) -- Systematic surveillance for enterovirus D68 (EV-D68) in a pediatric network turned up some surprising insights into this virus that jumped into the limelight with a 2014 outbreak tied to acute flaccid myelitis. Most of the children...


Another Biologic Reduces COPD Exacerbations
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115350.jpg"/> (MedPage Today) -- Mepolizumab (Nucala) helped prevent exacerbations of chronic obstructive pulmonary disease (COPD) when added to background triple inhaled therapy among patients with an eosinophilic phenotype, the phase III MATINEE trial showed...


Kids Were More Likely to Stop Inhaled Steroids for Asthma After Flovent's Exit
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115295.jpg"/> (MedPage Today) -- The market withdrawal of the brand-name asthma drug fluticasone propionate (Flovent) was linked to increased discontinuation of inhaled steroid therapy among children who had used the drug, a difference-in-differences analysis...


Race-Neutral Spirometry Equations Catch Missed Lung Abnormalities in Black Adults
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115294.jpg"/> (MedPage Today) -- Race-neutral equations for assessing lung function appeared to catch more true-abnormal findings for Black patients than did previously standard race-adjusted spirometry equations, a study showed. In a large single center cohort...


Groups Decry Loss of Funding for 'Critically Important' GI Disease Network
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115251.jpg"/> (MedPage Today) -- Physicians and patient advocates are sounding the alarm after the NIH abruptly withdrew a grant renewal application for the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), the only clinical care network...


FDA Approves New Option for Chronic Hives
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115194.jpg"/> (MedPage Today) -- The FDA approved dupilumab (Dupixent) for chronic spontaneous urticaria (CSU) in patients 12 years and older, the first new targeted drug for the inflammatory skin disease in over a decade, drugmakers Regeneron and Sanofi announced...


Best Time of Day for Asthma Inhaler?
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115122.jpg"/> (MedPage Today) -- For mild to moderate asthma, mid-afternoon dosing of inhaled beclomethasone suppressed nocturnal lung function worsening compared with other dosing strategies, a small open-label trial showed. A single 400-&#956;g dose at 3...


Inflammatory Markers Linked to Severe Attacks in Moderate Asthma
<img src="https://clf1.medpagetoday.com/media/images/115xxx/115060.jpg"/> (MedPage Today) -- Inflammatory markers boosted asthma attack prediction, potentially allowing intensification of treatment, according to a meta-analysis of patient-level data from randomized controlled trials. Greater risk of severe asthma attacks...